results from adding recombinant lh for assisted reproductive technology treatment: a randomized control trial
Authors
abstract
background: based on classical two-cell, two-gonadotropin theory, in the follicle, follicle-stimulating hormone (fsh) and luteinizing hormone (lh) put on their main effects on the granulosa and theca cells. lh is essential for androgens production. androgens are used for estradiol production by granulosa cells. profound suppression of lh concentrations in some normogonadotropic patients can cause several adverse effects. objective: the main clinical purpose of this study was that normoresponder women treated with controlled ovarian super ovulation for ivf or icsi may benefit from co-administration of rlh. materials and methods: 40 patients who were candidates for assisted reproductive technology (art) were randomly selected. in all patients long luteal protocol was used for ovulation induction. patients were randomly divided into two groups: group 1 (n=20) with standard long protocol (gnrh agonist) and r-fsh alone, group 2 (n=20) with standard long protocol (gnrh agonist) and r-fsh with r-lh. results were statistically analyzed and compared in two groups. results: the number of retrieved oocytes, mature oocytes, cleaved embryos, transferred embryos, estradiol levels in human chorionic gonadotropin (hcg) administration day, implantation rate and clinical pregnancy rate in group 2 were higher but not significantly different. conclusion: administration of rlh in late follicular phase had no beneficial effect on outcomes in young women with mean age of 31 years. maybe a greater sample size should be used to see the effects more accurately; also it is possible that rlh will be useful in older patients.
similar resources
P-165: Results of Adding Recombinant LH in Normoresponder Patients for Assisted Reproductive Technology Treatment: A Prospective Randomized Control Trial
Background: Based on classical two cell- two-gonadotropin theory, in the follicle, FSH and LH put on their main effects on the granulosa and theca cells. LH is essential for androgens production. Androgens as precursor, is used for estradiol production by granulosa cells under aromatase activity. Profound suppression of LH concentrations in some normogonadotropic patients can cause several adve...
full textResults from adding recombinant LH for assisted reproductive technology treatment: A randomized control trial
BACKGROUND Based on classical two-cell, two-gonadotropin theory, in the follicle, follicle-stimulating hormone (FSH) and luteinizing hormone (LH) put on their main effects on the granulosa and theca cells. LH is essential for androgens production. Androgens are used for estradiol production by granulosa cells. Profound suppression of LH concentrations in some normogonadotropic patients can caus...
full textP-174: Right to Treatment with Assisted Reproductive Technology
Background: Infertility leads to profound human suffering, particularly on the women. Women's lack of pregnancy is both physically and socially visible, especially in high fertility societies where women are typically blamed for reproductive failures, even in cases of male infertility. Childless women are more likely to be the victims of domestic violence and may also endure various forms ...
full textAssisted reproductive technology treatment outcomes.
Information on the outcomes of ART treatments in Ireland is not readily available to Irish practitioners. The data for hospital affiliated clinics has been made available for many years and is included in the hospital reports. We present a 10-year analysis of the Irish ART results voluntarily reported by six out of seven IVF clinics. The data was collected from published ESHRE reports and from ...
full textP-228: Low Dose HCG Adjunct to r-hFSH/GnRH Antagonist for Controlled Ovarian Stimulation in Assisted Reproductive Technology: A Prospective and Randomized Trial
Background: Deep suppression of LH in GnRH antagonist cycles may have detrimental effect on reproductive out come. It was hypnotized that adding LH activity via the administration of low dose HCG in late follicular phase shortened the duration of stimulation, decreased consumption of gonadotropin and increased estrogen levels. This study was designed to evaluate the effect of adding low dose HC...
full textMy Resources
Save resource for easier access later
Journal title:
international journal of reproductive biomedicineجلد ۱۲، شماره ۲، صفحات ۱۱۱-۰
Hosted on Doprax cloud platform doprax.com
copyright © 2015-2023